| Key Largo to Wayne (Michigan) | 1,197.36 mi (1,926.96 km) |
| Key Largo to Waynesboro (Pennsylvania) | 1,024.05 mi (1,648.06 km) |
| Key Largo to Waynesboro (Virginia) | 898.78 mi (1,446.45 km) |
| Key Largo to Weatherford (Oklahoma) | 1,302.39 mi (2,096.00 km) |
| Key Largo to Weatherford (Texas) | 1,172.52 mi (1,886.99 km) |
| Key Largo to Webb City (Missouri) | 1,172.34 mi (1,886.69 km) |
| Key Largo to Webster (Texas) | 951.88 mi (1,531.91 km) |
| Key Largo to Webster Groves (Missouri) | 1,096.48 mi (1,764.61 km) |
| Key Largo to Weddington (North Carolina) | 684.33 mi (1,101.32 km) |
| Key Largo to Weigelstown (Pennsylvania) | 1,047.63 mi (1,685.99 km) |
| Key Largo to Weirton (West Virginia) | 1,056.03 mi (1,699.52 km) |
| Key Largo to Wekiwa Springs (Florida) | 254.84 mi (410.12 km) |
| Key Largo to Welby (Colorado) | 1,745.82 mi (2,809.63 km) |
| Key Largo to Wellington (Colorado) | 1,776.41 mi (2,858.86 km) |
| Key Largo to Wellington (Florida) | 105.65 mi (170.02 km) |
