| Key West to Atlanta (Georgia) | 655.20 mi (1,054.45 km) |
| Key West to Houston (Texas) | 910.24 mi (1,464.90 km) |
| Key West to Washington (District of Columbia) | 1,029.14 mi (1,656.25 km) |
| Key West to Baltimore (Maryland) | 1,062.01 mi (1,709.15 km) |
| Key West to Dallas (Texas) | 1,070.08 mi (1,722.12 km) |
| Key West to St. Louis (Missouri) | 1,091.24 mi (1,756.18 km) |
| Key West to Philadelphia (Pennsylvania) | 1,134.51 mi (1,825.82 km) |
| Key West to Brooklyn (New York) | 1,199.88 mi (1,931.02 km) |
| Key West to New York (New York) | 1,203.19 mi (1,936.35 km) |
| Key West to Queens (New York) | 1,209.46 mi (1,946.44 km) |
| Key West to Detroit (Michigan) | 1,233.51 mi (1,985.14 km) |
| Key West to Chicago (Illinois) | 1,240.57 mi (1,996.51 km) |
| Key West to Boston (Massachusetts) | 1,370.21 mi (2,205.14 km) |
| Key West to Minneapolis (Minnesota) | 1,549.32 mi (2,493.39 km) |
| Key West to Denver (Colorado) | 1,702.14 mi (2,739.33 km) |
| Key West to Miami (Florida) | 129.26 mi (208.03 km) |
| Key West to Phoenix (Arizona) | 1,925.11 mi (3,098.17 km) |
| Key West to Las Vegas (Nevada) | 2,138.92 mi (3,442.26 km) |
| Key West to San Diego (California) | 2,205.72 mi (3,549.77 km) |
| Key West to Riverside (California) | 2,230.04 mi (3,588.91 km) |
| Key West to Los Angeles (California) | 2,289.04 mi (3,683.86 km) |
| Key West to Tampa (Florida) | 240.59 mi (387.19 km) |
| Key West to San Francisco (California) | 2,547.73 mi (4,100.17 km) |
| Key West to Portland (Oregon) | 2,686.64 mi (4,323.73 km) |
| Key West to Seattle (Washington) | 2,721.16 mi (4,379.28 km) |
