| Key West to Dixon (California) | 2,522.54 mi (4,059.63 km) |
| Key West to Dixon (Illinois) | 1,272.85 mi (2,048.45 km) |
| Key West to Dobbs Ferry (New York) | 1,224.42 mi (1,970.51 km) |
| Key West to Doctor Phillips (Florida) | 268.89 mi (432.73 km) |
| Key West to Dodge City (Kansas) | 1,407.48 mi (2,265.11 km) |
| Key West to Dolton (Illinois) | 1,225.42 mi (1,972.12 km) |
| Key West to Donna (Texas) | 1,021.57 mi (1,644.05 km) |
| Key West to Dorado (Puerto Rico) | 1,081.04 mi (1,739.76 km) |
| Key West to Doral (Florida) | 123.95 mi (199.48 km) |
| Key West to Doraville (Georgia) | 662.75 mi (1,066.59 km) |
| Key West to Dothan (Alabama) | 511.23 mi (822.75 km) |
| Key West to Douglas (Arizona) | 1,752.74 mi (2,820.76 km) |
| Key West to Douglas (Georgia) | 484.13 mi (779.13 km) |
| Key West to Douglasville (Georgia) | 657.94 mi (1,058.85 km) |
| Key West to Dover (Delaware) | 1,072.55 mi (1,726.11 km) |
