| Key West to Eagan (Minnesota) | 1,537.99 mi (2,475.16 km) |
| Key West to Eagle (Idaho) | 2,354.34 mi (3,788.95 km) |
| Key West to Eagle Mountain (Utah) | 2,056.11 mi (3,308.99 km) |
| Key West to Eagle Pass (Texas) | 1,188.88 mi (1,913.32 km) |
| Key West to Easley (South Carolina) | 710.16 mi (1,142.90 km) |
| Key West to East Bakersfield (California) | 2,332.57 mi (3,753.91 km) |
| Key West to East Bethel (Minnesota) | 1,571.76 mi (2,529.51 km) |
| Key West to East Chicago (Indiana) | 1,224.42 mi (1,970.52 km) |
| Key West to East Cleveland (Ohio) | 1,172.40 mi (1,886.79 km) |
| Key West to East Glenville (New York) | 1,341.01 mi (2,158.15 km) |
| Key West to East Grand Rapids (Michigan) | 1,288.63 mi (2,073.86 km) |
| Key West to East Hemet (California) | 2,202.38 mi (3,544.38 km) |
| Key West to East Highland Park (Virginia) | 935.57 mi (1,505.65 km) |
| Key West to East Honolulu (Hawaii) | 4,774.08 mi (7,683.14 km) |
| Key West to East Islip (New York) | 1,221.82 mi (1,966.33 km) |
