| Key West to Spout Springs (North Carolina) | 757.79 mi (1,219.55 km) |
| Key West to Spring (Texas) | 916.65 mi (1,475.20 km) |
| Key West to Spring Creek (Nevada) | 2,242.62 mi (3,609.14 km) |
| Key West to Spring Hill (Florida) | 274.51 mi (441.78 km) |
| Key West to Spring Hill (Tennessee) | 830.73 mi (1,336.93 km) |
| Key West to Spring Lake (North Carolina) | 752.35 mi (1,210.80 km) |
| Key West to Spring Valley (California) | 2,196.62 mi (3,535.12 km) |
| Key West to Spring Valley (Nevada) | 2,136.74 mi (3,438.76 km) |
| Key West to Spring Valley (New York) | 1,227.10 mi (1,974.83 km) |
| Key West to Springboro (Ohio) | 1,046.03 mi (1,683.42 km) |
| Key West to Springdale (Arkansas) | 1,088.78 mi (1,752.23 km) |
| Key West to Springdale (New Jersey) | 1,129.37 mi (1,817.55 km) |
| Key West to Springdale (Ohio) | 1,029.60 mi (1,656.98 km) |
| Key West to Springfield (Illinois) | 1,146.00 mi (1,844.31 km) |
| Key West to Springfield (Massachusetts) | 1,322.73 mi (2,128.72 km) |
