| Key West to St. George (Utah) | 2,062.33 mi (3,319.00 km) |
| Key West to St. Helens (Oregon) | 2,701.32 mi (4,347.36 km) |
| Key West to St. James (New York) | 1,231.93 mi (1,982.61 km) |
| Key West to St. John (Indiana) | 1,211.20 mi (1,949.24 km) |
| Key West to St. Joseph (Missouri) | 1,294.67 mi (2,083.57 km) |
| Key West to St. Louis (Missouri) | 1,091.24 mi (1,756.18 km) |
| Key West to St. Louis Park (Minnesota) | 1,550.69 mi (2,495.59 km) |
| Key West to St. Marys (Georgia) | 428.04 mi (688.87 km) |
| Key West to St. Marys (Pennsylvania) | 1,181.99 mi (1,902.23 km) |
| Key West to St. Matthews (Kentucky) | 972.33 mi (1,564.81 km) |
| Key West to St. Michael (Minnesota) | 1,573.67 mi (2,532.58 km) |
| Key West to St. Paul (Minnesota) | 1,544.58 mi (2,485.76 km) |
| Key West to St. Peter (Minnesota) | 1,528.10 mi (2,459.23 km) |
| Key West to St. Peters (Missouri) | 1,109.72 mi (1,785.92 km) |
| Key West to St. Petersburg (Florida) | 229.78 mi (369.80 km) |
