| Key West to Sugar Hill (Georgia) | 673.48 mi (1,083.86 km) |
| Key West to Sugar Land (Texas) | 919.80 mi (1,480.27 km) |
| Key West to Sugarland Run (Virginia) | 1,032.05 mi (1,660.93 km) |
| Key West to Sugarmill Woods (Florida) | 291.27 mi (468.75 km) |
| Key West to Suisun City (California) | 2,529.92 mi (4,071.51 km) |
| Key West to Suitland (Maryland) | 1,026.98 mi (1,652.76 km) |
| Key West to Sulphur (Louisiana) | 810.31 mi (1,304.07 km) |
| Key West to Sulphur Springs (Texas) | 1,024.16 mi (1,648.22 km) |
| Key West to Summerfield (Maryland) | 1,031.49 mi (1,660.02 km) |
| Key West to Summerfield (North Carolina) | 811.47 mi (1,305.94 km) |
| Key West to Summerlin South (Nevada) | 2,140.93 mi (3,445.49 km) |
| Key West to Summerville (South Carolina) | 590.91 mi (950.98 km) |
| Key West to Summit (Illinois) | 1,239.32 mi (1,994.50 km) |
| Key West to Summit (New Jersey) | 1,195.20 mi (1,923.49 km) |
| Key West to Sumner (Washington) | 2,707.20 mi (4,356.82 km) |
