| Knoxville to Savignano sul Rubicone | 4,826.36 mi (7,767.27 km) |
| Knoxville to Savona | 4,650.81 mi (7,484.76 km) |
| Knoxville to Scafati | 5,040.91 mi (8,112.56 km) |
| Knoxville to Scalea | 5,132.69 mi (8,260.27 km) |
| Knoxville to Scandiano | 4,736.05 mi (7,621.94 km) |
| Knoxville to Scandicci | 4,786.66 mi (7,703.39 km) |
| Knoxville to Schio | 4,725.71 mi (7,605.29 km) |
| Knoxville to Sciacca | 5,099.21 mi (8,206.38 km) |
| Knoxville to Scicli | 5,200.65 mi (8,369.64 km) |
| Knoxville to Scordia | 5,187.65 mi (8,348.72 km) |
| Knoxville to Scorze | 4,762.00 mi (7,663.71 km) |
| Knoxville to Sedico | 4,742.64 mi (7,632.54 km) |
| Knoxville to Sedriano | 4,632.66 mi (7,455.55 km) |
| Knoxville to Segni | 4,940.25 mi (7,950.56 km) |
| Knoxville to Segrate | 4,646.40 mi (7,477.65 km) |
