| Knoxville to Selargius | 4,854.94 mi (7,813.28 km) |
| Knoxville to Selvazzano Dentro | 4,754.97 mi (7,652.39 km) |
| Knoxville to Senago | 4,636.42 mi (7,461.60 km) |
| Knoxville to Senigallia | 4,874.91 mi (7,845.42 km) |
| Knoxville to Seravezza | 4,736.97 mi (7,623.41 km) |
| Knoxville to Seregno | 4,637.04 mi (7,462.59 km) |
| Knoxville to Seriate | 4,657.78 mi (7,495.98 km) |
| Knoxville to Sermoneta | 4,943.68 mi (7,956.09 km) |
| Knoxville to Serramanna | 4,838.00 mi (7,786.00 km) |
| Knoxville to Serravalle Pistoiese | 4,766.26 mi (7,670.56 km) |
| Knoxville to Sessa Aurunca | 4,996.98 mi (8,041.87 km) |
| Knoxville to Sesto Calende | 4,610.26 mi (7,419.49 km) |
| Knoxville to Sesto Fiorentino | 4,784.35 mi (7,699.67 km) |
| Knoxville to Sesto San Giovanni | 4,642.33 mi (7,471.10 km) |
| Knoxville to Sestri Levante | 4,691.42 mi (7,550.11 km) |
