| Kuopio to Sala Consilina | 1,631.74 mi (2,626.03 km) |
| Kuopio to Salemi | 1,842.07 mi (2,964.53 km) |
| Kuopio to Salerno | 1,623.84 mi (2,613.31 km) |
| Kuopio to Salo | 1,370.95 mi (2,206.33 km) |
| Kuopio to Salsomaggiore Terme | 1,431.43 mi (2,303.66 km) |
| Kuopio to Saluzzo | 1,492.18 mi (2,401.43 km) |
| Kuopio to Salzano | 1,346.00 mi (2,166.18 km) |
| Kuopio to Samarate | 1,404.61 mi (2,260.51 km) |
| Kuopio to San Benedetto del Tronto | 1,485.53 mi (2,390.74 km) |
| Kuopio to San Biagio di Callalta | 1,331.46 mi (2,142.78 km) |
| Kuopio to San Bonifacio | 1,369.61 mi (2,204.18 km) |
| Kuopio to San Casciano in Val di Pesa | 1,483.44 mi (2,387.37 km) |
| Kuopio to San Cataldo | 1,848.18 mi (2,974.36 km) |
| Kuopio to San Cesareo | 1,576.79 mi (2,537.60 km) |
| Kuopio to San Dona di Piave | 1,331.93 mi (2,143.54 km) |
