| Kuopio to Santeramo in Colle | 1,590.80 mi (2,560.14 km) |
| Kuopio to Santo Stefano di Magra | 1,474.22 mi (2,372.53 km) |
| Kuopio to Santo Stino di Livenza | 1,323.19 mi (2,129.47 km) |
| Kuopio to Sarezzo | 1,374.21 mi (2,211.57 km) |
| Kuopio to Sarno | 1,616.68 mi (2,601.79 km) |
| Kuopio to Saronno | 1,398.88 mi (2,251.28 km) |
| Kuopio to Sarzana | 1,476.49 mi (2,376.19 km) |
| Kuopio to Sassari | 1,720.38 mi (2,768.69 km) |
| Kuopio to Sasso Marconi | 1,434.37 mi (2,308.39 km) |
| Kuopio to Sassuolo | 1,433.07 mi (2,306.30 km) |
| Kuopio to Sava | 1,608.92 mi (2,589.30 km) |
| Kuopio to Saviano | 1,611.37 mi (2,593.24 km) |
| Kuopio to Savigliano | 1,488.89 mi (2,396.14 km) |
| Kuopio to Savignano sul Panaro | 1,432.93 mi (2,306.07 km) |
| Kuopio to Savignano sul Rubicone | 1,434.67 mi (2,308.88 km) |
