| Kuopio to Settimo Torinese | 1,455.92 mi (2,343.08 km) |
| Kuopio to Seveso | 1,395.72 mi (2,246.19 km) |
| Kuopio to Sezze | 1,593.58 mi (2,564.63 km) |
| Kuopio to Siano | 1,616.57 mi (2,601.62 km) |
| Kuopio to Siena | 1,502.81 mi (2,418.54 km) |
| Kuopio to Signa | 1,476.80 mi (2,376.68 km) |
| Kuopio to Silea | 1,335.01 mi (2,148.50 km) |
| Kuopio to Silvi Paese | 1,508.51 mi (2,427.71 km) |
| Kuopio to Sinalunga | 1,502.49 mi (2,418.02 km) |
| Kuopio to Siniscola | 1,709.68 mi (2,751.47 km) |
| Kuopio to Sinnai | 1,801.24 mi (2,898.81 km) |
| Kuopio to Siracusa | 1,859.70 mi (2,992.90 km) |
| Kuopio to Solaro | 1,398.58 mi (2,250.80 km) |
| Kuopio to Soliera | 1,418.57 mi (2,282.97 km) |
| Kuopio to Solofra | 1,612.43 mi (2,594.95 km) |
