| Kuopio to Spilamberto | 1,430.02 mi (2,301.39 km) |
| Kuopio to Spilimbergo | 1,294.25 mi (2,082.90 km) |
| Kuopio to Spinea | 1,347.81 mi (2,169.09 km) |
| Kuopio to Spoleto | 1,516.83 mi (2,441.09 km) |
| Kuopio to Spoltore | 1,514.46 mi (2,437.29 km) |
| Kuopio to Spresiano | 1,327.57 mi (2,136.52 km) |
| Kuopio to Squinzano | 1,601.65 mi (2,577.61 km) |
| Kuopio to Statte | 1,601.65 mi (2,577.60 km) |
| Kuopio to Stezzano | 1,384.91 mi (2,228.79 km) |
| Kuopio to Strada | 1,485.90 mi (2,391.33 km) |
| Kuopio to Stradella | 1,427.69 mi (2,297.65 km) |
| Kuopio to Striano | 1,617.35 mi (2,602.88 km) |
| Kuopio to Subiaco | 1,564.48 mi (2,517.78 km) |
| Kuopio to Sulmona | 1,544.53 mi (2,485.68 km) |
| Kuopio to Surbo | 1,603.06 mi (2,579.88 km) |
