| Kuopio to Sangeorz-Bai | 1,078.73 mi (1,736.05 km) |
| Kuopio to Sannicolau Mare | 1,195.16 mi (1,923.42 km) |
| Kuopio to Santana | 1,168.11 mi (1,879.89 km) |
| Kuopio to Satu Mare | 1,059.59 mi (1,705.25 km) |
| Kuopio to Scobinti | 1,071.97 mi (1,725.17 km) |
| Kuopio to Scornicesti | 1,272.04 mi (2,047.15 km) |
| Kuopio to Sebes | 1,180.94 mi (1,900.53 km) |
| Kuopio to Seini | 1,059.95 mi (1,705.83 km) |
| Kuopio to Sfantu-Gheorghe | 1,178.92 mi (1,897.28 km) |
| Kuopio to Sibiu | 1,189.55 mi (1,914.39 km) |
| Kuopio to Sighetu Marmatiei | 1,044.07 mi (1,680.27 km) |
| Kuopio to Sighisoara | 1,157.68 mi (1,863.11 km) |
| Kuopio to Simeria | 1,191.66 mi (1,917.80 km) |
| Kuopio to Sinaia | 1,214.96 mi (1,955.29 km) |
| Kuopio to Slatina | 1,282.44 mi (2,063.89 km) |
