| Laguna Niguel to Sceaux | 5,659.06 mi (9,107.38 km) |
| Laguna Niguel to Schiltigheim | 5,843.20 mi (9,403.73 km) |
| Laguna Niguel to Scionzier | 5,932.78 mi (9,547.88 km) |
| Laguna Niguel to Seclin | 5,599.17 mi (9,011.00 km) |
| Laguna Niguel to Sedan | 5,700.62 mi (9,174.26 km) |
| Laguna Niguel to Selestat | 5,851.51 mi (9,417.10 km) |
| Laguna Niguel to Sene | 5,538.83 mi (8,913.88 km) |
| Laguna Niguel to Senlis | 5,648.54 mi (9,090.45 km) |
| Laguna Niguel to Sens | 5,719.82 mi (9,205.15 km) |
| Laguna Niguel to Septemes-les-Vallons | 6,024.44 mi (9,695.40 km) |
| Laguna Niguel to Serris | 5,671.76 mi (9,127.82 km) |
| Laguna Niguel to Sete | 5,964.96 mi (9,599.67 km) |
| Laguna Niguel to Sevran | 5,659.77 mi (9,108.52 km) |
| Laguna Niguel to Sevres | 5,654.30 mi (9,099.72 km) |
| Laguna Niguel to Seynod | 5,926.07 mi (9,537.08 km) |
