| Laguna Niguel to Santa Venerina | 6,658.44 mi (10,715.73 km) |
| Laguna Niguel to Santeramo in Colle | 6,540.11 mi (10,525.28 km) |
| Laguna Niguel to Santo Stefano di Magra | 6,140.12 mi (9,881.58 km) |
| Laguna Niguel to Santo Stino di Livenza | 6,145.16 mi (9,889.68 km) |
| Laguna Niguel to Sarezzo | 6,072.04 mi (9,772.01 km) |
| Laguna Niguel to Sarno | 6,470.91 mi (10,413.92 km) |
| Laguna Niguel to Saronno | 6,036.03 mi (9,714.05 km) |
| Laguna Niguel to Sarzana | 6,144.13 mi (9,888.03 km) |
| Laguna Niguel to Sassari | 6,271.09 mi (10,092.34 km) |
| Laguna Niguel to Sasso Marconi | 6,170.93 mi (9,931.15 km) |
| Laguna Niguel to Sassuolo | 6,148.07 mi (9,894.37 km) |
| Laguna Niguel to Sava | 6,587.23 mi (10,601.12 km) |
| Laguna Niguel to Saviano | 6,462.25 mi (10,399.98 km) |
| Laguna Niguel to Savigliano | 6,039.61 mi (9,719.81 km) |
| Laguna Niguel to Savignano sul Panaro | 6,159.61 mi (9,912.93 km) |
