| Laguna Niguel to Entroncamento | 5,666.21 mi (9,118.88 km) |
| Laguna Niguel to Ericeira | 5,646.65 mi (9,087.41 km) |
| Laguna Niguel to Ermezinde | 5,589.54 mi (8,995.49 km) |
| Laguna Niguel to Esmoriz | 5,597.26 mi (9,007.92 km) |
| Laguna Niguel to Espinho | 5,594.42 mi (9,003.36 km) |
| Laguna Niguel to Esposende | 5,566.72 mi (8,958.77 km) |
| Laguna Niguel to Estarreja | 5,608.32 mi (9,025.72 km) |
| Laguna Niguel to Estoril | 5,658.19 mi (9,105.98 km) |
| Laguna Niguel to Estremoz | 5,729.71 mi (9,221.08 km) |
| Laguna Niguel to Evora | 5,728.24 mi (9,218.71 km) |
| Laguna Niguel to Fafe | 5,595.64 mi (9,005.31 km) |
| Laguna Niguel to Falagueira | 5,663.34 mi (9,114.26 km) |
| Laguna Niguel to Famalicao | 5,582.59 mi (8,984.31 km) |
| Laguna Niguel to Fanzeres | 5,592.33 mi (8,999.98 km) |
| Laguna Niguel to Faro | 5,792.46 mi (9,322.06 km) |
