| Laguna Niguel to Sangeorgiu de Mures | 6,423.70 mi (10,337.95 km) |
| Laguna Niguel to Sangeorz-Bai | 6,380.13 mi (10,267.82 km) |
| Laguna Niguel to Sannicolau Mare | 6,353.98 mi (10,225.74 km) |
| Laguna Niguel to Santana | 6,360.78 mi (10,236.69 km) |
| Laguna Niguel to Satu Mare | 6,312.00 mi (10,158.19 km) |
| Laguna Niguel to Scobinti | 6,431.65 mi (10,350.74 km) |
| Laguna Niguel to Scornicesti | 6,543.29 mi (10,530.40 km) |
| Laguna Niguel to Sebes | 6,436.44 mi (10,358.45 km) |
| Laguna Niguel to Seini | 6,324.16 mi (10,177.75 km) |
| Laguna Niguel to Sfantu-Gheorghe | 6,496.52 mi (10,455.13 km) |
| Laguna Niguel to Sibiu | 6,460.85 mi (10,397.73 km) |
| Laguna Niguel to Sighetu Marmatiei | 6,328.18 mi (10,184.23 km) |
| Laguna Niguel to Sighisoara | 6,451.39 mi (10,382.51 km) |
| Laguna Niguel to Simeria | 6,428.76 mi (10,346.09 km) |
| Laguna Niguel to Sinaia | 6,521.58 mi (10,495.48 km) |
