| Laguna Niguel to El Astillero | 5,685.23 mi (9,149.50 km) |
| Laguna Niguel to El Ejido | 6,021.37 mi (9,690.45 km) |
| Laguna Niguel to El Escorial | 5,797.76 mi (9,330.59 km) |
| Laguna Niguel to El Espinar | 5,786.79 mi (9,312.94 km) |
| Laguna Niguel to El Molar | 5,812.89 mi (9,354.95 km) |
| Laguna Niguel to El Prat de Llobregat | 6,006.12 mi (9,665.92 km) |
| Laguna Niguel to El Puerto de Santa Maria | 5,884.81 mi (9,470.69 km) |
| Laguna Niguel to El Viso del Alcor | 5,872.20 mi (9,450.40 km) |
| Laguna Niguel to Elche | 6,040.71 mi (9,721.58 km) |
| Laguna Niguel to Elda | 6,026.96 mi (9,699.45 km) |
| Laguna Niguel to Elgoibar | 5,747.47 mi (9,249.67 km) |
| Laguna Niguel to Erandio | 5,722.12 mi (9,208.86 km) |
| Laguna Niguel to Ermua | 5,745.47 mi (9,246.43 km) |
| Laguna Niguel to Esparraguera | 5,987.47 mi (9,635.90 km) |
| Laguna Niguel to Espartinas | 5,855.14 mi (9,422.93 km) |
