| Laguna de Duero to Spello | 892.50 mi (1,436.34 km) |
| Laguna de Duero to Spilamberto | 818.58 mi (1,317.37 km) |
| Laguna de Duero to Spilimbergo | 929.10 mi (1,495.24 km) |
| Laguna de Duero to Spinea | 885.48 mi (1,425.04 km) |
| Laguna de Duero to Spoleto | 893.23 mi (1,437.52 km) |
| Laguna de Duero to Spoltore | 967.80 mi (1,557.53 km) |
| Laguna de Duero to Spresiano | 893.98 mi (1,438.71 km) |
| Laguna de Duero to Squinzano | 1,186.24 mi (1,909.07 km) |
| Laguna de Duero to Statte | 1,140.64 mi (1,835.68 km) |
| Laguna de Duero to Stezzano | 770.41 mi (1,239.85 km) |
| Laguna de Duero to Strada | 825.94 mi (1,329.22 km) |
| Laguna de Duero to Stradella | 743.62 mi (1,196.74 km) |
| Laguna de Duero to Striano | 1,001.79 mi (1,612.23 km) |
| Laguna de Duero to Subiaco | 916.95 mi (1,475.69 km) |
| Laguna de Duero to Sulmona | 958.65 mi (1,542.80 km) |
