| Lake Monticello to Enterprise (Nevada) | 2,028.00 mi (3,263.75 km) |
| Lake Monticello to Enumclaw (Washington) | 2,279.96 mi (3,669.24 km) |
| Lake Monticello to Ephrata (Pennsylvania) | 194.08 mi (312.34 km) |
| Lake Monticello to Erie (Colorado) | 1,436.66 mi (2,312.08 km) |
| Lake Monticello to Erie (Pennsylvania) | 304.21 mi (489.57 km) |
| Lake Monticello to Erlanger (Kentucky) | 346.69 mi (557.94 km) |
| Lake Monticello to Escanaba (Michigan) | 703.26 mi (1,131.78 km) |
| Lake Monticello to Escondido (California) | 2,187.62 mi (3,520.63 km) |
| Lake Monticello to Española (New Mexico) | 1,531.46 mi (2,464.65 km) |
| Lake Monticello to Essex (Maryland) | 139.49 mi (224.48 km) |
| Lake Monticello to Essex Junction (Vermont) | 528.42 mi (850.41 km) |
| Lake Monticello to Estelle (Louisiana) | 874.70 mi (1,407.69 km) |
| Lake Monticello to Estero (Florida) | 819.39 mi (1,318.68 km) |
| Lake Monticello to Euclid (Ohio) | 304.86 mi (490.63 km) |
| Lake Monticello to Eufaula (Alabama) | 566.95 mi (912.41 km) |
