| Lake Monticello to Scottsboro (Alabama) | 485.70 mi (781.66 km) |
| Lake Monticello to Scottsdale (Arizona) | 1,891.48 mi (3,044.05 km) |
| Lake Monticello to Scranton (Pennsylvania) | 279.27 mi (449.45 km) |
| Lake Monticello to Seabrook (Maryland) | 108.45 mi (174.54 km) |
| Lake Monticello to Seabrook (Texas) | 1,116.47 mi (1,796.79 km) |
| Lake Monticello to Seaford (New York) | 320.73 mi (516.16 km) |
| Lake Monticello to Seagoville (Texas) | 1,087.71 mi (1,750.50 km) |
| Lake Monticello to Seal Beach (California) | 2,227.69 mi (3,585.13 km) |
| Lake Monticello to Searcy (Arkansas) | 765.71 mi (1,232.29 km) |
| Lake Monticello to Seaside (California) | 2,370.99 mi (3,815.73 km) |
| Lake Monticello to SeaTac (Washington) | 2,294.49 mi (3,692.62 km) |
| Lake Monticello to Seattle (Washington) | 2,295.77 mi (3,694.69 km) |
| Lake Monticello to Sebastian (Florida) | 711.51 mi (1,145.07 km) |
| Lake Monticello to Sebring (Florida) | 743.97 mi (1,197.31 km) |
| Lake Monticello to Secaucus (New Jersey) | 301.49 mi (485.20 km) |
