| Lake Monticello to Southern Pines (North Carolina) | 197.71 mi (318.18 km) |
| Lake Monticello to Southfield (Michigan) | 408.24 mi (657.00 km) |
| Lake Monticello to Southgate (Michigan) | 392.40 mi (631.50 km) |
| Lake Monticello to Southlake (Texas) | 1,111.34 mi (1,788.53 km) |
| Lake Monticello to Spanaway (Washington) | 2,300.35 mi (3,702.05 km) |
| Lake Monticello to Spanish Fork (Utah) | 1,784.19 mi (2,871.37 km) |
| Lake Monticello to Spanish Lake (Missouri) | 645.91 mi (1,039.49 km) |
| Lake Monticello to Spanish Springs (Nevada) | 2,209.87 mi (3,556.44 km) |
| Lake Monticello to Sparks (Nevada) | 2,213.35 mi (3,562.05 km) |
| Lake Monticello to Spartanburg (South Carolina) | 286.75 mi (461.48 km) |
| Lake Monticello to Spearfish (South Dakota) | 1,393.62 mi (2,242.82 km) |
| Lake Monticello to Speedway (Indiana) | 445.08 mi (716.29 km) |
| Lake Monticello to Spencer (Iowa) | 952.25 mi (1,532.49 km) |
| Lake Monticello to Spokane (Washington) | 2,068.46 mi (3,328.87 km) |
| Lake Monticello to Spokane Valley (Washington) | 2,059.24 mi (3,314.02 km) |
