| Lake Shore to Oswego (Illinois) | 647.93 mi (1,042.75 km) |
| Lake Shore to Oswego (New York) | 300.46 mi (483.54 km) |
| Lake Shore to Otsego (Minnesota) | 972.38 mi (1,564.90 km) |
| Lake Shore to Ottawa (Illinois) | 668.57 mi (1,075.96 km) |
| Lake Shore to Ottawa (Kansas) | 1,009.10 mi (1,624.00 km) |
| Lake Shore to Ottumwa (Iowa) | 851.55 mi (1,370.44 km) |
| Lake Shore to Overland (Missouri) | 746.22 mi (1,200.93 km) |
| Lake Shore to Overland Park (Kansas) | 975.77 mi (1,570.35 km) |
| Lake Shore to Overlea (Maryland) | 18.12 mi (29.16 km) |
| Lake Shore to Oviedo (Florida) | 770.07 mi (1,239.31 km) |
| Lake Shore to Owasso (Oklahoma) | 1,073.13 mi (1,727.03 km) |
| Lake Shore to Owatonna (Minnesota) | 929.15 mi (1,495.32 km) |
| Lake Shore to Owensboro (Kentucky) | 582.44 mi (937.35 km) |
| Lake Shore to Owings Mills (Maryland) | 26.80 mi (43.13 km) |
| Lake Shore to Owosso (Michigan) | 482.20 mi (776.03 km) |
