| Lake Shore to Santa Rosa (California) | 2,462.57 mi (3,963.13 km) |
| Lake Shore to Santaquin (Utah) | 1,869.93 mi (3,009.36 km) |
| Lake Shore to Santee (California) | 2,285.73 mi (3,678.53 km) |
| Lake Shore to Sapulpa (Oklahoma) | 1,093.05 mi (1,759.10 km) |
| Lake Shore to Saraland (Alabama) | 869.04 mi (1,398.59 km) |
| Lake Shore to Sarasota (Florida) | 884.42 mi (1,423.33 km) |
| Lake Shore to Sarasota Springs (Florida) | 884.80 mi (1,423.94 km) |
| Lake Shore to Saratoga (California) | 2,450.30 mi (3,943.37 km) |
| Lake Shore to Saratoga Springs (New York) | 308.09 mi (495.83 km) |
| Lake Shore to Saratoga Springs (Utah) | 1,872.05 mi (3,012.77 km) |
| Lake Shore to Sartell (Minnesota) | 1,008.09 mi (1,622.37 km) |
| Lake Shore to Satellite Beach (Florida) | 790.81 mi (1,272.68 km) |
| Lake Shore to Sauk Rapids (Minnesota) | 1,004.57 mi (1,616.70 km) |
| Lake Shore to Sault Ste. Marie (Michigan) | 647.17 mi (1,041.52 km) |
| Lake Shore to Savage (Minnesota) | 948.92 mi (1,527.14 km) |
