| Lake Shore to Scottsboro (Alabama) | 611.24 mi (983.69 km) |
| Lake Shore to Scottsdale (Arizona) | 1,989.86 mi (3,202.37 km) |
| Lake Shore to Scranton (Pennsylvania) | 164.82 mi (265.25 km) |
| Lake Shore to Seabrook (Maryland) | 21.23 mi (34.16 km) |
| Lake Shore to Seabrook (Texas) | 1,241.92 mi (1,998.67 km) |
| Lake Shore to Seaford (New York) | 192.10 mi (309.15 km) |
| Lake Shore to Seagoville (Texas) | 1,204.86 mi (1,939.04 km) |
| Lake Shore to Seal Beach (California) | 2,320.64 mi (3,734.71 km) |
| Lake Shore to Searcy (Arkansas) | 879.55 mi (1,415.49 km) |
| Lake Shore to Seaside (California) | 2,453.04 mi (3,947.78 km) |
| Lake Shore to SeaTac (Washington) | 2,339.41 mi (3,764.91 km) |
| Lake Shore to Seattle (Washington) | 2,340.02 mi (3,765.90 km) |
| Lake Shore to Sebastian (Florida) | 815.14 mi (1,311.84 km) |
| Lake Shore to Sebring (Florida) | 852.55 mi (1,372.04 km) |
| Lake Shore to Secaucus (New Jersey) | 172.90 mi (278.26 km) |
