| Lake Shore to Superior (Colorado) | 1,522.67 mi (2,450.50 km) |
| Lake Shore to Superior (Wisconsin) | 945.02 mi (1,520.87 km) |
| Lake Shore to Surprise (Arizona) | 2,021.44 mi (3,253.19 km) |
| Lake Shore to Susanville (California) | 2,320.79 mi (3,734.95 km) |
| Lake Shore to Sussex (Wisconsin) | 670.54 mi (1,079.13 km) |
| Lake Shore to Suwanee (Georgia) | 546.25 mi (879.11 km) |
| Lake Shore to Swansea (Illinois) | 726.90 mi (1,169.83 km) |
| Lake Shore to Sweetwater (Florida) | 947.87 mi (1,525.45 km) |
| Lake Shore to Sweetwater (Texas) | 1,411.95 mi (2,272.32 km) |
| Lake Shore to Sycamore (Illinois) | 669.99 mi (1,078.25 km) |
| Lake Shore to Sylacauga (Alabama) | 681.18 mi (1,096.26 km) |
| Lake Shore to Sylvania (Ohio) | 420.29 mi (676.39 km) |
| Lake Shore to Syosset (New York) | 197.48 mi (317.81 km) |
| Lake Shore to Syracuse (New York) | 272.66 mi (438.80 km) |
| Lake Shore to Syracuse (Utah) | 1,872.63 mi (3,013.71 km) |
