| Lawrence to Southern Pines (North Carolina) | 910.83 mi (1,465.84 km) |
| Lawrence to Southfield (Michigan) | 673.18 mi (1,083.38 km) |
| Lawrence to Southgate (Michigan) | 670.59 mi (1,079.21 km) |
| Lawrence to Southlake (Texas) | 428.09 mi (688.94 km) |
| Lawrence to Spanaway (Washington) | 1,473.06 mi (2,370.65 km) |
| Lawrence to Spanish Fork (Utah) | 875.01 mi (1,408.20 km) |
| Lawrence to Spanish Lake (Missouri) | 272.22 mi (438.09 km) |
| Lawrence to Spanish Springs (Nevada) | 1,301.59 mi (2,094.71 km) |
| Lawrence to Sparks (Nevada) | 1,304.65 mi (2,099.63 km) |
| Lawrence to Spartanburg (South Carolina) | 786.10 mi (1,265.10 km) |
| Lawrence to Spearfish (South Dakota) | 582.95 mi (938.17 km) |
| Lawrence to Speedway (Indiana) | 484.76 mi (780.15 km) |
| Lawrence to Spencer (Iowa) | 289.36 mi (465.68 km) |
| Lawrence to Spokane (Washington) | 1,260.14 mi (2,027.99 km) |
| Lawrence to Spokane Valley (Washington) | 1,251.38 mi (2,013.90 km) |
