| Lawrence to Superior (Colorado) | 531.92 mi (856.04 km) |
| Lawrence to Superior (Wisconsin) | 558.06 mi (898.11 km) |
| Lawrence to Surprise (Arizona) | 1,021.94 mi (1,644.65 km) |
| Lawrence to Susanville (California) | 1,346.90 mi (2,167.62 km) |
| Lawrence to Sussex (Wisconsin) | 466.45 mi (750.67 km) |
| Lawrence to Suwanee (Georgia) | 707.52 mi (1,138.64 km) |
| Lawrence to Swansea (Illinois) | 285.76 mi (459.89 km) |
| Lawrence to Sweetwater (Florida) | 1,255.28 mi (2,020.17 km) |
| Lawrence to Sweetwater (Texas) | 533.07 mi (857.90 km) |
| Lawrence to Sycamore (Illinois) | 404.38 mi (650.79 km) |
| Lawrence to Sylacauga (Alabama) | 641.64 mi (1,032.62 km) |
| Lawrence to Sylvania (Ohio) | 636.97 mi (1,025.10 km) |
| Lawrence to Syosset (New York) | 1,157.83 mi (1,863.34 km) |
| Lawrence to Syracuse (New York) | 1,033.56 mi (1,663.35 km) |
| Lawrence to Syracuse (Utah) | 899.79 mi (1,448.07 km) |
