| Le Grand-Saconnex to Sestu | 502.19 mi (808.20 km) |
| Le Grand-Saconnex to Settimo Torinese | 110.09 mi (177.17 km) |
| Le Grand-Saconnex to Seveso | 150.75 mi (242.60 km) |
| Le Grand-Saconnex to Sezze | 475.90 mi (765.89 km) |
| Le Grand-Saconnex to Siano | 569.94 mi (917.23 km) |
| Le Grand-Saconnex to Siena | 325.43 mi (523.72 km) |
| Le Grand-Saconnex to Signa | 296.41 mi (477.03 km) |
| Le Grand-Saconnex to Silea | 299.52 mi (482.03 km) |
| Le Grand-Saconnex to Silvi Paese | 469.51 mi (755.61 km) |
| Le Grand-Saconnex to Sinalunga | 345.49 mi (556.01 km) |
| Le Grand-Saconnex to Siniscola | 430.19 mi (692.33 km) |
| Le Grand-Saconnex to Sinnai | 503.70 mi (810.62 km) |
| Le Grand-Saconnex to Siracusa | 789.46 mi (1,270.52 km) |
| Le Grand-Saconnex to Solaro | 148.86 mi (239.57 km) |
| Le Grand-Saconnex to Soliera | 254.72 mi (409.93 km) |
