| Le Puy-en-Velay to Schiltigheim | 306.57 mi (493.38 km) |
| Le Puy-en-Velay to Scionzier | 146.74 mi (236.15 km) |
| Le Puy-en-Velay to Seclin | 382.42 mi (615.44 km) |
| Le Puy-en-Velay to Sedan | 325.63 mi (524.06 km) |
| Le Puy-en-Velay to Selestat | 279.28 mi (449.45 km) |
| Le Puy-en-Velay to Sene | 362.45 mi (583.31 km) |
| Le Puy-en-Velay to Senlis | 294.09 mi (473.29 km) |
| Le Puy-en-Velay to Sens | 219.77 mi (353.68 km) |
| Le Puy-en-Velay to Septemes-les-Vallons | 135.25 mi (217.67 km) |
| Le Puy-en-Velay to Serris | 268.50 mi (432.11 km) |
| Le Puy-en-Velay to Sete | 113.55 mi (182.75 km) |
| Le Puy-en-Velay to Sevran | 276.21 mi (444.51 km) |
| Le Puy-en-Velay to Sevres | 272.86 mi (439.13 km) |
| Le Puy-en-Velay to Seynod | 122.03 mi (196.39 km) |
| Le Puy-en-Velay to Seysses | 166.11 mi (267.32 km) |
