| Le Puy-en-Velay to Savona | 231.42 mi (372.44 km) |
| Le Puy-en-Velay to Scafati | 614.02 mi (988.17 km) |
| Le Puy-en-Velay to Scalea | 705.78 mi (1,135.85 km) |
| Le Puy-en-Velay to Scandiano | 334.77 mi (538.75 km) |
| Le Puy-en-Velay to Scandicci | 371.28 mi (597.52 km) |
| Le Puy-en-Velay to Schio | 365.36 mi (587.99 km) |
| Le Puy-en-Velay to Sciacca | 705.75 mi (1,135.80 km) |
| Le Puy-en-Velay to Scicli | 801.16 mi (1,289.34 km) |
| Le Puy-en-Velay to Scordia | 780.64 mi (1,256.31 km) |
| Le Puy-en-Velay to Scorze | 401.11 mi (645.53 km) |
| Le Puy-en-Velay to Sedico | 403.94 mi (650.08 km) |
| Le Puy-en-Velay to Sedriano | 248.95 mi (400.65 km) |
| Le Puy-en-Velay to Segni | 513.68 mi (826.69 km) |
| Le Puy-en-Velay to Segrate | 264.85 mi (426.23 km) |
| Le Puy-en-Velay to Selargius | 482.51 mi (776.52 km) |
