| Le Puy-en-Velay to Selvazzano Dentro | 385.00 mi (619.60 km) |
| Le Puy-en-Velay to Senago | 257.67 mi (414.69 km) |
| Le Puy-en-Velay to Senigallia | 469.70 mi (755.91 km) |
| Le Puy-en-Velay to Seravezza | 320.84 mi (516.34 km) |
| Le Puy-en-Velay to Seregno | 261.43 mi (420.73 km) |
| Le Puy-en-Velay to Seriate | 286.53 mi (461.13 km) |
| Le Puy-en-Velay to Sermoneta | 516.86 mi (831.80 km) |
| Le Puy-en-Velay to Serramanna | 465.83 mi (749.68 km) |
| Le Puy-en-Velay to Serravalle Pistoiese | 351.45 mi (565.61 km) |
| Le Puy-en-Velay to Sessa Aurunca | 570.35 mi (917.90 km) |
| Le Puy-en-Velay to Sesto Calende | 235.25 mi (378.60 km) |
| Le Puy-en-Velay to Sesto Fiorentino | 370.29 mi (595.92 km) |
| Le Puy-en-Velay to Sesto San Giovanni | 262.12 mi (421.85 km) |
| Le Puy-en-Velay to Sestri Levante | 275.83 mi (443.91 km) |
| Le Puy-en-Velay to Sestu | 477.88 mi (769.07 km) |
