| Le Puy-en-Velay to Spilamberto | 351.37 mi (565.47 km) |
| Le Puy-en-Velay to Spilimbergo | 441.35 mi (710.28 km) |
| Le Puy-en-Velay to Spinea | 403.44 mi (649.27 km) |
| Le Puy-en-Velay to Spoleto | 465.46 mi (749.08 km) |
| Le Puy-en-Velay to Spoltore | 541.71 mi (871.81 km) |
| Le Puy-en-Velay to Spresiano | 408.74 mi (657.80 km) |
| Le Puy-en-Velay to Squinzano | 784.83 mi (1,263.06 km) |
| Le Puy-en-Velay to Statte | 741.26 mi (1,192.94 km) |
| Le Puy-en-Velay to Stezzano | 283.14 mi (455.68 km) |
| Le Puy-en-Velay to Strada | 380.85 mi (612.92 km) |
| Le Puy-en-Velay to Stradella | 264.23 mi (425.24 km) |
| Le Puy-en-Velay to Striano | 613.53 mi (987.38 km) |
| Le Puy-en-Velay to Subiaco | 509.06 mi (819.25 km) |
| Le Puy-en-Velay to Sulmona | 543.31 mi (874.37 km) |
| Le Puy-en-Velay to Surbo | 789.77 mi (1,271.02 km) |
