| Lecce to Sala Consilina | 135.14 mi (217.49 km) |
| Lecce to Salemi | 336.78 mi (541.99 km) |
| Lecce to Salerno | 180.40 mi (290.32 km) |
| Lecce to Salo | 529.16 mi (851.60 km) |
| Lecce to Salsomaggiore Terme | 517.88 mi (833.45 km) |
| Lecce to Saluzzo | 618.86 mi (995.97 km) |
| Lecce to Salzano | 470.77 mi (757.64 km) |
| Lecce to Samarate | 597.13 mi (960.98 km) |
| Lecce to San Benedetto del Tronto | 284.85 mi (458.41 km) |
| Lecce to San Biagio di Callalta | 470.23 mi (756.76 km) |
| Lecce to San Bonifacio | 492.82 mi (793.12 km) |
| Lecce to San Casciano in Val di Pesa | 424.83 mi (683.70 km) |
| Lecce to San Cataldo | 299.61 mi (482.18 km) |
| Lecce to San Cesareo | 297.23 mi (478.35 km) |
| Lecce to San Dona di Piave | 461.54 mi (742.78 km) |
