| Lecce to Selvazzano Dentro | 474.50 mi (763.63 km) |
| Lecce to Senago | 581.91 mi (936.49 km) |
| Lecce to Senigallia | 344.10 mi (553.78 km) |
| Lecce to Seravezza | 477.82 mi (768.97 km) |
| Lecce to Seregno | 581.96 mi (936.57 km) |
| Lecce to Seriate | 563.39 mi (906.68 km) |
| Lecce to Sermoneta | 282.86 mi (455.23 km) |
| Lecce to Serramanna | 494.07 mi (795.13 km) |
| Lecce to Serravalle Pistoiese | 448.49 mi (721.78 km) |
| Lecce to Sessa Aurunca | 229.68 mi (369.63 km) |
| Lecce to Sesto Calende | 607.65 mi (977.92 km) |
| Lecce to Sesto Fiorentino | 430.47 mi (692.78 km) |
| Lecce to Sesto San Giovanni | 575.96 mi (926.92 km) |
| Lecce to Sestri Levante | 523.43 mi (842.38 km) |
| Lecce to Sestu | 486.77 mi (783.38 km) |
