| Lefkada to Somma Lombardo | 776.63 mi (1,249.86 km) |
| Lefkada to Somma Vesuviana | 361.47 mi (581.72 km) |
| Lefkada to Sommacampagna | 681.41 mi (1,096.63 km) |
| Lefkada to Sona | 683.49 mi (1,099.98 km) |
| Lefkada to Sondrio | 751.64 mi (1,209.64 km) |
| Lefkada to Sora | 424.52 mi (683.21 km) |
| Lefkada to Sorbolo | 673.80 mi (1,084.37 km) |
| Lefkada to Soresina | 714.96 mi (1,150.62 km) |
| Lefkada to Sorisole | 741.24 mi (1,192.91 km) |
| Lefkada to Sorrento | 358.52 mi (576.98 km) |
| Lefkada to Sorso | 656.27 mi (1,056.17 km) |
| Lefkada to Sortino | 323.89 mi (521.25 km) |
| Lefkada to Soverato Marina | 220.75 mi (355.26 km) |
| Lefkada to Sovicille | 582.80 mi (937.93 km) |
| Lefkada to Spello | 510.17 mi (821.03 km) |
