| Leighton Buzzard to Savignano sul Rubicone | 808.26 mi (1,300.77 km) |
| Leighton Buzzard to Savona | 672.90 mi (1,082.93 km) |
| Leighton Buzzard to Scafati | 1,054.05 mi (1,696.32 km) |
| Leighton Buzzard to Scalea | 1,146.38 mi (1,844.91 km) |
| Leighton Buzzard to Scandiano | 725.55 mi (1,167.66 km) |
| Leighton Buzzard to Scandicci | 785.61 mi (1,264.31 km) |
| Leighton Buzzard to Schio | 693.34 mi (1,115.83 km) |
| Leighton Buzzard to Sciacca | 1,198.41 mi (1,928.65 km) |
| Leighton Buzzard to Scicli | 1,285.92 mi (2,069.49 km) |
| Leighton Buzzard to Scordia | 1,260.12 mi (2,027.97 km) |
| Leighton Buzzard to Scorze | 726.79 mi (1,169.66 km) |
| Leighton Buzzard to Sedico | 701.99 mi (1,129.74 km) |
| Leighton Buzzard to Sedriano | 623.79 mi (1,003.89 km) |
| Leighton Buzzard to Segni | 955.25 mi (1,537.33 km) |
| Leighton Buzzard to Segrate | 634.00 mi (1,020.32 km) |
