| Leighton Buzzard to Selargius | 993.47 mi (1,598.83 km) |
| Leighton Buzzard to Selvazzano Dentro | 723.92 mi (1,165.03 km) |
| Leighton Buzzard to Senago | 623.96 mi (1,004.17 km) |
| Leighton Buzzard to Senigallia | 855.33 mi (1,376.52 km) |
| Leighton Buzzard to Seravezza | 742.29 mi (1,194.60 km) |
| Leighton Buzzard to Seregno | 622.71 mi (1,002.15 km) |
| Leighton Buzzard to Seriate | 638.05 mi (1,026.84 km) |
| Leighton Buzzard to Sermoneta | 961.52 mi (1,547.41 km) |
| Leighton Buzzard to Serramanna | 977.49 mi (1,573.12 km) |
| Leighton Buzzard to Serravalle Pistoiese | 766.51 mi (1,233.58 km) |
| Leighton Buzzard to Sessa Aurunca | 1,008.92 mi (1,623.70 km) |
| Leighton Buzzard to Sesto Calende | 600.18 mi (965.89 km) |
| Leighton Buzzard to Sesto Fiorentino | 781.78 mi (1,258.15 km) |
| Leighton Buzzard to Sesto San Giovanni | 629.76 mi (1,013.51 km) |
| Leighton Buzzard to Sestri Levante | 701.69 mi (1,129.26 km) |
