| Leighton Buzzard to Sestu | 989.05 mi (1,591.72 km) |
| Leighton Buzzard to Settimo Torinese | 606.15 mi (975.50 km) |
| Leighton Buzzard to Seveso | 621.01 mi (999.42 km) |
| Leighton Buzzard to Sezze | 966.88 mi (1,556.04 km) |
| Leighton Buzzard to Siano | 1,056.84 mi (1,700.82 km) |
| Leighton Buzzard to Siena | 813.39 mi (1,309.03 km) |
| Leighton Buzzard to Signa | 781.21 mi (1,257.24 km) |
| Leighton Buzzard to Silea | 729.83 mi (1,174.54 km) |
| Leighton Buzzard to Silvi Paese | 945.13 mi (1,521.03 km) |
| Leighton Buzzard to Sinalunga | 831.61 mi (1,338.34 km) |
| Leighton Buzzard to Siniscola | 924.84 mi (1,488.38 km) |
| Leighton Buzzard to Sinnai | 991.38 mi (1,595.46 km) |
| Leighton Buzzard to Siracusa | 1,286.39 mi (2,070.25 km) |
| Leighton Buzzard to Solaro | 620.74 mi (998.98 km) |
| Leighton Buzzard to Soliera | 725.93 mi (1,168.27 km) |
