| Leon to Spello | 923.41 mi (1,486.08 km) |
| Leon to Spilamberto | 839.45 mi (1,350.96 km) |
| Leon to Spilimbergo | 941.08 mi (1,514.52 km) |
| Leon to Spinea | 900.81 mi (1,449.72 km) |
| Leon to Spoleto | 925.50 mi (1,489.45 km) |
| Leon to Spoltore | 1,001.33 mi (1,611.49 km) |
| Leon to Spresiano | 907.56 mi (1,460.58 km) |
| Leon to Squinzano | 1,227.05 mi (1,974.75 km) |
| Leon to Statte | 1,181.51 mi (1,901.46 km) |
| Leon to Stezzano | 782.36 mi (1,259.09 km) |
| Leon to Strada | 853.20 mi (1,373.09 km) |
| Leon to Stradella | 759.33 mi (1,222.02 km) |
| Leon to Striano | 1,043.45 mi (1,679.27 km) |
| Leon to Subiaco | 953.76 mi (1,534.93 km) |
| Leon to Sulmona | 994.44 mi (1,600.40 km) |
