| Lepe to Spello | 1,119.03 mi (1,800.90 km) |
| Lepe to Spilamberto | 1,072.98 mi (1,726.79 km) |
| Lepe to Spilimbergo | 1,199.17 mi (1,929.87 km) |
| Lepe to Spinea | 1,149.80 mi (1,850.43 km) |
| Lepe to Spoleto | 1,115.90 mi (1,795.86 km) |
| Lepe to Spoltore | 1,184.00 mi (1,905.46 km) |
| Lepe to Spresiano | 1,161.68 mi (1,869.54 km) |
| Lepe to Squinzano | 1,371.79 mi (2,207.68 km) |
| Lepe to Statte | 1,327.39 mi (2,136.23 km) |
| Lepe to Stezzano | 1,044.78 mi (1,681.41 km) |
| Lepe to Strada | 1,064.77 mi (1,713.58 km) |
| Lepe to Stradella | 1,011.64 mi (1,628.07 km) |
| Lepe to Striano | 1,190.71 mi (1,916.27 km) |
| Lepe to Subiaco | 1,125.20 mi (1,810.84 km) |
| Lepe to Sulmona | 1,168.36 mi (1,880.29 km) |
