| Letchworth to Sestu | 983.12 mi (1,582.17 km) |
| Letchworth to Settimo Torinese | 597.08 mi (960.91 km) |
| Letchworth to Seveso | 610.00 mi (981.69 km) |
| Letchworth to Sezze | 956.42 mi (1,539.20 km) |
| Letchworth to Siano | 1,045.79 mi (1,683.03 km) |
| Letchworth to Siena | 802.82 mi (1,292.01 km) |
| Letchworth to Signa | 770.42 mi (1,239.86 km) |
| Letchworth to Silea | 716.47 mi (1,153.05 km) |
| Letchworth to Silvi Paese | 933.25 mi (1,501.92 km) |
| Letchworth to Sinalunga | 820.81 mi (1,320.97 km) |
| Letchworth to Siniscola | 917.64 mi (1,476.79 km) |
| Letchworth to Sinnai | 985.34 mi (1,585.75 km) |
| Letchworth to Siracusa | 1,277.01 mi (2,055.14 km) |
| Letchworth to Solaro | 609.80 mi (981.38 km) |
| Letchworth to Soliera | 714.39 mi (1,149.69 km) |
