| Littleton to Elyria (Ohio) | 1,206.85 mi (1,942.25 km) |
| Littleton to Emeryville (California) | 937.65 mi (1,509.00 km) |
| Littleton to Emmaus (Pennsylvania) | 1,555.11 mi (2,502.71 km) |
| Littleton to Emporia (Kansas) | 480.77 mi (773.73 km) |
| Littleton to Encinitas (California) | 816.61 mi (1,314.21 km) |
| Littleton to Endicott (New York) | 1,515.97 mi (2,439.71 km) |
| Littleton to Endwell (New York) | 1,518.04 mi (2,443.04 km) |
| Littleton to Englewood (Colorado) | 4.04 mi (6.50 km) |
| Littleton to Englewood (Florida) | 1,565.76 mi (2,519.85 km) |
| Littleton to Englewood (New Jersey) | 1,631.22 mi (2,625.20 km) |
| Littleton to Englewood (Ohio) | 1,098.29 mi (1,767.53 km) |
| Littleton to Enid (Oklahoma) | 446.93 mi (719.27 km) |
| Littleton to Ennis (Texas) | 686.30 mi (1,104.50 km) |
| Littleton to Ensley (Florida) | 1,179.72 mi (1,898.58 km) |
| Littleton to Enterprise (Alabama) | 1,217.16 mi (1,958.83 km) |
