| Lowes Island to Olympia Heights (Florida) | 936.72 mi (1,507.51 km) |
| Lowes Island to Omaha (Nebraska) | 997.33 mi (1,605.05 km) |
| Lowes Island to On Top of the World Designated Place (Florida) | 742.33 mi (1,194.66 km) |
| Lowes Island to Onalaska (Wisconsin) | 790.14 mi (1,271.61 km) |
| Lowes Island to Oneida (New York) | 292.01 mi (469.94 km) |
| Lowes Island to Oneonta (New York) | 264.09 mi (425.02 km) |
| Lowes Island to Ontario (California) | 2,242.66 mi (3,609.22 km) |
| Lowes Island to Ontario (Oregon) | 2,057.66 mi (3,311.48 km) |
| Lowes Island to Opa-locka (Florida) | 923.87 mi (1,486.82 km) |
| Lowes Island to Opelika (Alabama) | 629.26 mi (1,012.70 km) |
| Lowes Island to Opelousas (Louisiana) | 1,020.23 mi (1,641.90 km) |
| Lowes Island to Orange (California) | 2,260.01 mi (3,637.14 km) |
| Lowes Island to Orange (Texas) | 1,115.88 mi (1,795.83 km) |
| Lowes Island to Orange City (Florida) | 733.95 mi (1,181.18 km) |
| Lowes Island to Orangeburg (South Carolina) | 430.73 mi (693.19 km) |
