| Lowes Island to Seymour (Tennessee) | 414.19 mi (666.58 km) |
| Lowes Island to Shady Hills (Florida) | 793.24 mi (1,276.59 km) |
| Lowes Island to Shafter (California) | 2,294.12 mi (3,692.02 km) |
| Lowes Island to Shaker Heights (Ohio) | 277.61 mi (446.77 km) |
| Lowes Island to Shakopee (Minnesota) | 916.53 mi (1,475.02 km) |
| Lowes Island to Sharon (Pennsylvania) | 224.62 mi (361.49 km) |
| Lowes Island to Sharonville (Ohio) | 378.18 mi (608.62 km) |
| Lowes Island to Shasta Lake (California) | 2,364.22 mi (3,804.85 km) |
| Lowes Island to Shawnee (Kansas) | 935.41 mi (1,505.39 km) |
| Lowes Island to Shawnee (Oklahoma) | 1,106.74 mi (1,781.13 km) |
| Lowes Island to Sheboygan (Wisconsin) | 627.45 mi (1,009.78 km) |
| Lowes Island to Shelby (North Carolina) | 347.27 mi (558.88 km) |
| Lowes Island to Shelbyville (Indiana) | 451.71 mi (726.96 km) |
| Lowes Island to Shelbyville (Kentucky) | 428.98 mi (690.37 km) |
| Lowes Island to Shelbyville (Tennessee) | 556.77 mi (896.03 km) |
