| Lowes Island to St. Simons (Georgia) | 589.41 mi (948.57 km) |
| Lowes Island to Stafford (Texas) | 1,222.53 mi (1,967.47 km) |
| Lowes Island to Stallings (North Carolina) | 327.48 mi (527.03 km) |
| Lowes Island to Stamford (Connecticut) | 245.78 mi (395.55 km) |
| Lowes Island to Stanford (California) | 2,409.91 mi (3,878.37 km) |
| Lowes Island to Stanton (California) | 2,269.30 mi (3,652.08 km) |
| Lowes Island to Star (Idaho) | 2,035.32 mi (3,275.53 km) |
| Lowes Island to Starkville (Mississippi) | 746.05 mi (1,200.65 km) |
| Lowes Island to State College (Pennsylvania) | 123.41 mi (198.61 km) |
| Lowes Island to Staten Island (New York) | 200.38 mi (322.48 km) |
| Lowes Island to Statesboro (Georgia) | 519.51 mi (836.06 km) |
| Lowes Island to Statesville (North Carolina) | 296.79 mi (477.64 km) |
| Lowes Island to Staunton (Virginia) | 110.79 mi (178.30 km) |
| Lowes Island to Steamboat Springs (Colorado) | 1,561.16 mi (2,512.45 km) |
| Lowes Island to Steiner Ranch (Texas) | 1,307.78 mi (2,104.68 km) |
