| Luxembourg to Sacile | 388.11 mi (624.60 km) |
| Luxembourg to Sala Consilina | 785.45 mi (1,264.06 km) |
| Luxembourg to Salemi | 879.50 mi (1,415.42 km) |
| Luxembourg to Salerno | 745.62 mi (1,199.96 km) |
| Luxembourg to Salo | 344.64 mi (554.65 km) |
| Luxembourg to Salsomaggiore Terme | 377.32 mi (607.23 km) |
| Luxembourg to Saluzzo | 349.02 mi (561.70 km) |
| Luxembourg to Salzano | 396.29 mi (637.76 km) |
| Luxembourg to Samarate | 302.34 mi (486.58 km) |
| Luxembourg to San Benedetto del Tronto | 589.99 mi (949.50 km) |
| Luxembourg to San Biagio di Callalta | 397.45 mi (639.63 km) |
| Luxembourg to San Bonifacio | 377.29 mi (607.19 km) |
| Luxembourg to San Casciano in Val di Pesa | 475.95 mi (765.96 km) |
| Luxembourg to San Cataldo | 924.43 mi (1,487.72 km) |
| Luxembourg to San Cesareo | 626.76 mi (1,008.68 km) |
