| Luxembourg to Sestu | 727.16 mi (1,170.24 km) |
| Luxembourg to Settimo Torinese | 318.72 mi (512.93 km) |
| Luxembourg to Seveso | 307.77 mi (495.31 km) |
| Luxembourg to Sezze | 652.56 mi (1,050.20 km) |
| Luxembourg to Siano | 736.65 mi (1,185.52 km) |
| Luxembourg to Siena | 500.02 mi (804.71 km) |
| Luxembourg to Signa | 466.23 mi (750.32 km) |
| Luxembourg to Silea | 396.16 mi (637.56 km) |
| Luxembourg to Silvi Paese | 619.35 mi (996.75 km) |
| Luxembourg to Sinalunga | 515.83 mi (830.15 km) |
| Luxembourg to Siniscola | 647.98 mi (1,042.82 km) |
| Luxembourg to Sinnai | 728.05 mi (1,171.68 km) |
| Luxembourg to Siracusa | 979.46 mi (1,576.29 km) |
| Luxembourg to Solaro | 308.42 mi (496.36 km) |
| Luxembourg to Soliera | 404.85 mi (651.54 km) |
