| Luxembourg to Spello | 553.48 mi (890.74 km) |
| Luxembourg to Spilamberto | 419.27 mi (674.75 km) |
| Luxembourg to Spilimbergo | 394.59 mi (635.03 km) |
| Luxembourg to Spinea | 399.77 mi (643.37 km) |
| Luxembourg to Spoleto | 567.51 mi (913.32 km) |
| Luxembourg to Spoltore | 625.40 mi (1,006.48 km) |
| Luxembourg to Spresiano | 388.24 mi (624.82 km) |
| Luxembourg to Squinzano | 858.74 mi (1,382.00 km) |
| Luxembourg to Statte | 824.12 mi (1,326.29 km) |
| Luxembourg to Stezzano | 318.93 mi (513.27 km) |
| Luxembourg to Strada | 483.54 mi (778.19 km) |
| Luxembourg to Stradella | 346.17 mi (557.11 km) |
| Luxembourg to Striano | 732.34 mi (1,178.59 km) |
| Luxembourg to Subiaco | 627.26 mi (1,009.48 km) |
| Luxembourg to Sulmona | 642.62 mi (1,034.19 km) |
